1999 SEQUENCE OF 1ST HUMAN CHROMOSOME (22) 'NATURE' JOURNAL DNA GENETICS SCIENCE - $550 - (Beverly Hills, CA)
[SCIENCE MILESTONES, DNA, HUMAN GENOME PROJECT ] "NATURE : International Journal of Science" London. Macmillan Magazines. 1999. First Edition. Original magazine style scientific journal in wraps as issued. Slight hints of wear at spine tips. Contents clean and sharp. Complete with folding chromosome chart. Overall, fine. THIS ISSUE NOTABLE FOR CONTAINING THE FIRST SEQUENCE OF A HUMAN CHROMOSOME. This issue is scarce in the market as it is now well known as being a key and landmark work in the annals of scientific achievement. (From the article abstract) Knowledge of the complete genomic DNA sequence of an organism allows a systematic approach to defining its genetic components. The genomic sequence provides access to the complete structures of all genes, including those without known function, their control elements, and, by inference, the proteins they encode, as well as all other biologically important sequences. Furthermore, the sequence is a rich and permanent source of information for the design of further biological studies of the organism and for the study of evolution through cross-species sequence comparison. The power of this approach has been amply demonstrated by the determination of the sequences of a number of microbial and model organisms, The next step is to obtain the complete sequence of the entire human genome. Here we report the sequence of the euchromatic part of human chromosome 22. The sequence obtained consists of 12 contiguous segments spanning 33.4 megabases, contains at least 545 genes and 134 pseudogenes, and provides the first view of the complex chromosomal landscapes that will be found in the rest of the genome.Please email any questions -
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